Liverpool Hospital Emergency Department


This is generally now agreed to be impractical in beta-blocker overdose. The dosing required  generally exceeds hospital stocks. It has positive inotropic and chronotropic effects similar to  beta adrenergic agonists. 

  • Calcium channel Overdose
  • B- Blocker overdose  


  • 1mg/1ml 

Dosage and Administration: 

  • Patient must be in a monitored area
  • Bolus dose of 5mg IV
  • Dosage can be repeated every 5 minutes after that
  • If a clinical response is observed consider an infusion at 2-5mg/hr in 5% dextrose

Side Effects: 

  • Nausea and vomiting
  • Hyperglycaemia
  • Hypokalaemia 

Pit Falls: 

  • Amount of glucagon required to obtain effect will likely exceed hospital stores  rapidly
  • Failure to administer adequate dosage
  • This is not regarded as a first line agent and its use is superseded by high dose  euglycaemic therapy.